除了小分子抑制剂,核酸技术也开始在ACH治疗中得到应用。Ribomic开发的RBM-007,通过限制FGF2和FGFR3激活变体之间的过度相互作用发挥功能。2期临床结果显示,RBM-007的疗效与Vosoritide相近(1.5厘米/年),甚至有一名受试者年增长5厘米,且该试验中包括2周一次的注射频率,是当前在研药物中最长的给药间隔。
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eBay announced that it is cutting about 800 jobs from its global staff. "We are taking steps to reinvest across our business and align our structure with our strategic priorities, which will affect certain roles across our workforce," the retailer said in a statement as reported by Bloomberg. This move will see about 6 percent of eBay's current full-time workers laid off. Bloomberg noted that eBay would continue hiring in "key areas" but did not specify what those fields are.